Timeline
The Founding of R2
David A. Present, M.D. and Cherine Eldumiati Plumaker, General Partners of Pansend Life Sciences, co-founded R2 Technologies and licensed exclusive intellectual property from Massachusetts General Hospital and Blossom Innovations on their patented method of CryomodulationTM.
Research
R2 begins the research and development of the technology around CryomodulationTM.
FDA Clearance
R2 receives clearance for the removal of benign lesions of the skin.
FDA Clearance
R2 receives clearance for their next-generation system.
First Published Manuscript from founders
Lasers in Surgery and Medicine introduces the treatment of benign lesions utilizing a novel dermal cooling system.
Strategic Partnership
R2 closes strategic investment and commercial partnership with Huadong Medicine Co., Ltd.
FDA Clearance
R2 receives expanded indication for the temporary reduction of pain, swelling and inflammation.
Glacial Rx and Glacial Spa
treatments available
First commercial installations and treatments underway in select countries.
FDA Clearance
R2 receives expanded indication when dermabrasion tips are used, the intended use includes general dermabrasion, scar revision, acne scar revision, and tattoo removal.
Scientific Founders

R. ROX ANDERSON, M.D.

DIETER MANSTEIN, M.D., PhD

HENRY H. L. CHAN, M.D., PhD
R2 Team
Tim has 17 years of commercial experience in the aesthetic medical device industry which includes key leadership roles at Reliant Technologies and ZELTIQ. He was at the forefront of the successful product launches of Fraxel and CoolSculpting as well as the growth and scaling of those two ventures from start-up to IPO/acquisition. R2 will be Tim’s third successive company delivering a game-changing product to market that originated in the labs of world-renowned serial inventors, Drs. Rox Anderson, Dieter Manstein and Henry Chan.
Tim is a native of Ohio. He received his BBA in Marketing from Ohio University in 1997 and his MBA from Campbell University in 1999. He has been involved in various youth mentorship and philanthropic organizations. He is a member of the Ohio University Executive Advisory Board, he’s a sponsor of the Ohio University Select Leaders Program and he’s an Ambassador for the Gratitude Network.

TIM HOLT
President & CEO
Kristine has dedicated her 25-year career to cryobiology research and the development of cold-based medical devices. She held a leadership position at ZELTIQ and dedicated the last decade to aesthetic applications for cold therapies.

KRISTINE TATSUTANI
Chief Science & Technology Officer
Casey has 20+ years’ experience leading high performing teams in sales operations, customer service, and logistics in the medical aesthetics and life science industries. Most recently with ZELTIQ where he helped to launch the CoolSculpting brand and commercial programs.

CASEY TORREZ
Vice President of Operations

ANGELL HAIFLICH
Vice President of Finance and Administration
Peggy has held progressive marketing roles at several large aesthetic companies and has worked with notable aesthetic physicians, leading KOL management and strategic product marketing.

PEGGY CHUNG
SR. Director of Marketing
Nearly 2 decades of influence & top sales performance in the medical device industry across breakthrough & disruptive technol ogies. Maximized CoolSculpting adoption at Zeltiq, Allergan & AbbVie, and now leading North American sales at R2 Technologies.

BRYAN STECKEL
Director of Sales, North America
Board of Directors
David A. Present, MD, Chairman, Founder, and General Partner, Pansend Life Sciences, LLC
Cherine Eldumiati Plumaker, Vice Chairman, Founder, and General Partner, Pansend Life Sciences, LLC
Irina Erenburg, PhD, Founder and Chief Executive Officer, Blossom Innovations, LLC
Yuhang Zhao, PhD, MBA, Adviser to China Grand, Inc.
Seth Orlow, MD, PhD, Professor and Chair of Dermatology, NYU School of Medicine
Tim Holt, MBA, President and Chief Executive Officer, R2 Technologies, Inc.
Dovid Tu, APAC General Manager
Exclusive Partners
Allies of Skin
Founded in 2016 by Nicolas Travis, a Forbes “30 Under 30,” and sold in more than 29 markets worldwide and counting, cult-favorite brand Allies of Skin creates multi-benefit formulas for all skin types that work harder and smarter. Each multitasking product takes clinically proven actives and combines them with innovative, optimally concentrated, biocompatible ingredients that work synergistically to provide maximum results. Allies of Skin’s clinical-grade formulas are clean and effective, smart and sophisticated, and packed with the greatest amount of active ingredients possible, winning numerous prestigious beauty awards from magazines including Allure, Harper’s Bazaar, Teen Vogue and InStyle.

Huadong Medicine Company, Limited
Huadong Medicine Co., Ltd., is a leading Chinese pharmaceutical company based in Hangzhou, China. Founded in 1993, Huadong Medicine has fully integrated R&D, manufacturing, distribution, sales and marketing capabilities. Huadong Medicine’s product portfolio and pipeline are specialized in oncology, immunology, nephrology and diabetes. The company’s annual revenue in 2019 exceeded 5 billion USD. Huadong Medicine has 12,000 employees, among which 1,000 are dedicated to R&D. Huadong Medicine possesses one of the most extensive commercial coverage and marketing capabilities in China. Huadong Medicine Company – Patient Centered, Science Driven.

Recent News
Content Hub
At R2 Technologies, we believe in empowering our providers with the most up to date information. Find links to latest news, upcoming events, and so many more resources like product guides and on-demand webinars!
Content HubContact us
2603 Camino Ramon, Suite 200, Bishop Ranch 3,
San Ramon, CA 94583
Email ‒ info@r2technologies.com
Call ‒ (925) 378-4400
801 Brickell Ave., Suite # 711
Miami FL, 33131