The Founding of R2
David A. Present, M.D. and Cherine Eldumiati Plumaker, General Partners of Pansend Life Sciences, co-founded R2 Technologies and licensed exclusive intellectual property from Massachusetts General Hospital and Blossom Innovations on their patented method of CryomodulationTM.
R2 begins the research and development of the technology around CryomodulationTM.
R2 receives clearance for the removal of benign lesions of the skin.
R2 receives clearance for their next-generation system.
First Published Manuscript from founders
Lasers in Surgery and Medicine introduces the treatment of benign lesions utilizing a novel dermal cooling system.
R2 closes strategic investment and commercial partnership with Huadong Medicine Co., Ltd.
R2 receives expanded indication for the temporary reduction of pain, swelling and inflammation.
Glacial Rx and Glacial Spa
First commercial installations and treatments underway in select countries.
R2 receives expanded indication when dermabrasion tips are used, the intended use includes general dermabrasion, scar revision, acne scar revision, and tattoo removal.
R. ROX ANDERSON, M.D.
DIETER MANSTEIN, M.D., PhD
HENRY H. L. CHAN, M.D., PhD
Tim has 17 years of commercial experience in the aesthetic medical device industry which includes key leadership roles at Reliant Technologies and ZELTIQ. He was at the forefront of the successful product launches of Fraxel and CoolSculpting as well as the growth and scaling of those two ventures from start-up to IPO/acquisition. R2 will be Tim’s third successive company delivering a game-changing product to market that originated in the labs of world-renowned serial inventors, Drs. Rox Anderson, Dieter Manstein and Henry Chan.
Tim is a native of Ohio. He received his BBA in Marketing from Ohio University in 1997 and his MBA from Campbell University in 1999. He has been involved in various youth mentorship and philanthropic organizations. He is a member of the Ohio University Executive Advisory Board, he’s a sponsor of the Ohio University Select Leaders Program and he’s an Ambassador for the Gratitude Network.
President & CEO
Kristine has dedicated her 25-year career to cryobiology research and the development of cold-based medical devices. She held a leadership position at ZELTIQ and dedicated the last decade to aesthetic applications for cold therapies.
Chief Science & Technology Officer
Casey has 20+ years’ experience leading high performing teams in sales operations, customer service, and logistics in the medical aesthetics and life science industries. Most recently with ZELTIQ where he helped to launch the CoolSculpting brand and commercial programs.
Vice President of Operations
Vice President of Finance and Administration
Board of Directors
David A. Present, MD, Chairman, Founder, and General Partner, Pansend Life Sciences, LLC
Cherine Eldumiati Plumaker, Vice Chairman, Founder, and General Partner, Pansend Life Sciences, LLC
Irina Erenburg, PhD, Founder and Chief Executive Officer, Blossom Innovations, LLC
Yuhang Zhao, PhD, MBA, Adviser to China Grand, Inc.
Seth Orlow, MD, PhD, Professor and Chair of Dermatology, NYU School of Medicine
Tim Holt, MBA, President and Chief Executive Officer, R2 Technologies, Inc.
Dovid Tu, APAC General Manager
Allies of Skin
Founded in 2016 by Nicolas Travis, a Forbes “30 Under 30,” and sold in more than 29 markets worldwide and counting, cult-favorite brand Allies of Skin creates multi-benefit formulas for all skin types that work harder and smarter. Each multitasking product takes clinically proven actives and combines them with innovative, optimally concentrated, biocompatible ingredients that work synergistically to provide maximum results. Allies of Skin’s clinical-grade formulas are clean and effective, smart and sophisticated, and packed with the greatest amount of active ingredients possible, winning numerous prestigious beauty awards from magazines including Allure, Harper’s Bazaar, Teen Vogue and InStyle.
Huadong Medicine Company, Limited
Huadong Medicine Co., Ltd., is a leading Chinese pharmaceutical company based in Hangzhou, China. Founded in 1993, Huadong Medicine has fully integrated R&D, manufacturing, distribution, sales and marketing capabilities. Huadong Medicine’s product portfolio and pipeline are specialized in oncology, immunology, nephrology and diabetes. The company’s annual revenue in 2019 exceeded 5 billion USD. Huadong Medicine has 12,000 employees, among which 1,000 are dedicated to R&D. Huadong Medicine possesses one of the most extensive commercial coverage and marketing capabilities in China. Huadong Medicine Company – Patient Centered, Science Driven.
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